Joining the lab

We strive to create an inclusive environment and look to support our staff throughout their time with us. We have a broad view of what “success” looks like and consider all suitably qualified applicants. The University of Bristol has an excellent career development framework for research staff called “Bristol Clear” https://www.bristol.ac.uk/staffdevelopment/academic/researchstaffhub/ and research staff are very strongly encouraged to engage with that scheme. In addition to direct support with in the lab, graduate students receive significant support through individual programmes, academic progression panels, and our Bristol Doctoral College. We also support attendance at research conferences, training workshops, and many other career development opportunities.

Graduate students

All of our studentships are advertised through findaphd.com

We currently have an opportunity that we hope to be advertised through two of our graduate programmes, SWBio and GW4 BioMed. These webpages have full details of eligibility and the funding offered as well as the application process. Please do get in touch by email if you would like to discuss the project further but all applications must be made through the routes indicated on the programme websites.

  • Project available for September 2022 entry:

Primary cilia assembly, disassembly, and cell proliferation

Our work addresses three overlapping areas: secretory pathway function, membrane-microtubule dynamics, and formation and function or primary cilia. Primary (non-motile) cilia are hair-like extensions present on almost all animal cells that act as antenna for extracellular signals and are fundamental to proper metazoan development and ongoing health. In animals, primary cilia are required for key signalling pathways including Hedgehog and TGF beta. Defects in cilia are linked to many inherited human diseases and more recent data has identified a key role for ciliary signalling in wound healing including resolving bone fractures. This has led to the proposal that assembly and disassembly of primary cilia and ciliary signalling could be attractive targets to intervene in fibrosis and scarring. Our work is focused on the role of the microtubule motor dynein-2 in these processes. Cilia extend from the mother centriole which inherently links dynein-2 function to the centrioles and centrosomes. In this collaborative project between Bristol and Exeter, you will use in vitro biochemistry, high resolution microscopy, and phosphoproteomics to explore this.

The Wellcome Trust Programme in Dynamic Molecular Cell Biology is typically advertised in winter and provides a route to join the lab through application to the programme overall.

These programmes are currently the only route by which we are able to accept students owing to limits on our lab capacity.

Postdoctoral applicants

All of our postdoctoral opportunities are advertised on the University of Bristol website and jobs.ac.uk.

Potential postdocs might also wish to consider fellowship routes such as EMBO, HFSP, Newton, or Marie Curie schemes. We welcome enquiries for suitable candidates who should write including a cv and details of specific project interests which match on to our current work. We will consider supporting the most able candidates for these but please ensure you are eligible.

Unfortunately we are currently very tight on space and so unlikely to be able to accept any new lab members until late 2022.

Undergraduate students
We are unable to accept interns or summer students for more than one week unless their stay in the lab is funded. This is to ensure fair access for all regardless of ability to work without getting any income. For undergraduate students this could be through relevant Wellcome Trust, Nuffield, Biochemical Society, or British Society for Cell Biology schemes.

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